BMX-IN-1 Inhibitor

Name: BMX-IN-1 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5754635
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5754635

BMX-IN-1 is a selective and irreversible bone marrow tyrosine kinase on chromosome X (BMX)inhibitor that targets Cys496 in the BMX ATP binding domain with an IC50 of 8nM. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

BMX-IN-1, Inhibitor

Full Product Name

BMX-IN-1

Product Gene Name

BMX-IN-1, inhibitor

Product Synonym Names

BMX kinase inhibitor

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

524.59

Solubility

DMSO: 100mg/mL (190.63mM) Need ultrasonic
DMF: 10mg/mL (19.06mM) Need ultrasonic
H2O: <0.1mg/mL (insoluble)
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C29H24N4O4S

SMILES

O=C1N(C2=C(C=C1)C=NC3=CC=C(C4=CC=C(NS(=O)(C)=O)C=C4)C=C32)C5=CC=C(C)C(NC(C=C)=O)=C5

CAS Number

1431525-23-3

Target & IC50

BMX: ic50 8nM
BTK: ic50 10.4nM

Product Categories/Family for BMX-IN-1, inhibitor

Angiogenesis; BTK; Tyrosine Kinase/Adaptors

Product References and Citations for BMX-IN-1, inhibitor

Feiyang Liu, et al. Discovery of a Selective Irreversible BMX Inhibitor for Prostate Cancer. ACS Chem. Biol., DOI: 10.1021/cb4000629
Feiyang Liu, et al. Discovery of a Selective Irreversible BMX Inhibitor for Prostate Cancer. ACS Chem. Biol., DOI: 10.1021/cb4000629

Other Notes

Small volumes of BMX-IN-1, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BMX-IN-1 purchase

MBS5754635 is an inhibitor targeting BMX-IN-1.