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C87 Inhibitor – C 87

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5754654

C87 is a novel small-molecule TNFalpha inhibitor. It inhibits TNFalpha-induced cytotoxicity (IC50: 8.73uM). More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
C 87 (C87), Inhibitor
Full Product Name
C 87
Product Gene Name
C87, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
502.93
Solubility
DMSO: 9.33mg/mL (18.55mM) Need ultrasonic and warming
H2O: <0.1mg/mL (insoluble)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C24H15ClN6O3S
SMILES
O=C(N(C1=NC(C2=CC=CC=C2)=CS1)N=C/3C4=CC=CC=C4)C3=N\NC5=CC=C(Cl)C([N+]([O-])=O)=C5
CAS Number
332420-90-3
Target & IC50
TNFalpha-induced cytotoxicity: ic50 8.73uM

Structure of C87, inhibitor

C87 Inhibitor – Cat# MBS5754654

Product References and Citations for C87, inhibitor

Ma L, et al. A novel small-molecule tumor necrosis factor alpha inhibitor attenuates inflammation in a hepatitis mouse model. J Biol Chem. 2014 May 2;289(18):12457-66.
Ma L, et al. A novel small-molecule tumor necrosis factor alpha inhibitor attenuates inflammation in a hepatitis mouse model. J Biol Chem. 2014 May 2;289(18):12457-66.

Other Notes

Small volumes of C87, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for C87 purchase

MBS5754654 is an inhibitor targeting C87. Also known as C 87.
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