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C527 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5754655

C527 is a pan inhibitor of the DUB enzyme with high potency for the USP1/UAF1 complex (IC50: 0.88 uM). More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
C527, Inhibitor
Full Product Name
C527
Product Gene Name
C527, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
293.25
Solubility
DMSO: <1mg/mL (insoluble or slightly soluble)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C17H8FNO3
SMILES
O=C1C2=C(N=C(C3=CC=C(F)C=C3)O2)C(C4=CC=CC=C41)=O
CAS Number
192718-06-2
Target & IC50
USP1: ic50 0.88uM

Structure of C527, inhibitor

C527 Inhibitor – Cat# MBS5754655

Product References and Citations for C527, inhibitor

Mistry H, et al. Small-molecule inhibitors of USP1 target ID1 degradation in leukemic cells. Mol Cancer Ther. 2013 Dec;12(12):2651-62.
Mistry H, et al. Small-molecule inhibitors of USP1 target ID1 degradation in leukemic cells. Mol Cancer Ther. 2013 Dec;12(12):2651-62.

Other Notes

Small volumes of C527, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for C527 purchase

MBS5754655 is an inhibitor targeting C527.
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