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CC-90003 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5754676

MBS5754676 is an inhibitor targeting CC-90003. CC-90003 is a selective inhibitor of ERK 1/2 with antitumor activity. More details

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Product Documentation
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Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CC-90003, Inhibitor
Full Product Name
CC-90003
Product Gene Name
CC-90003, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
458.44
Solubility
DMSO: 125mg/mL (272.66mM)
H2O: <0.1mg/mL (insoluble)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C22H21F3N6O2
SMILES
C=CC(NC1=CC(C)=CC=C1NC2=NC(NC3=CC(OC)=NC=C3C)=NC=C2C(F)(F)F)=O
CAS Number
1621999-82-3
Target & IC50
ERK1
ERK2

Product Categories/Family for CC-90003, inhibitor

MAPK; ERK

Structure of CC-90003, inhibitor

CC-90003 Inhibitor – Cat# MBS5754676

Product References and Citations for CC-90003, inhibitor

Monica M. Mita, et al. A phase Ia study of CC-90003, a selective extracellular signal-regulated kinase (ERK) inhibitor, in patients with relapsed or refractory BRAF or RAS-mutant tumors. Journal of Clinical Oncology 35, no. 15_suppl (May 20 2017) 2577-2577.
Monica M. Mita, et al. A phase Ia study of CC-90003, a selective extracellular signal-regulated kinase (ERK) inhibitor, in patients with relapsed or refractory BRAF or RAS-mutant tumors. Journal of Clinical Oncology 35, no. 15_suppl (May 20 2017) 2577-2577.

Other Notes

Small volumes of CC-90003, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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