• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Chroman 1 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5754712

MBS5754712 is an inhibitor targeting Chroman 1. Chroman 1 is an inhibitor of ROCK2 (IC50: 1nM). More details

Please Inquire
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Chroman 1, Inhibitor
Full Product Name
Chroman 1
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
436.5
Solubility
DMSO: 50mg/mL (114.55mM)
H2O: <0.1mg/mL (insoluble)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C24H28N4O4
SMILES
O=C([C@@H]1COC2=CC=C(OC)C=C2C1)NC3=CC=C(C4=CNN=C4)C=C3OCCN(C)C
CAS Number
1273579-40-0
Target & IC50
ROCK2: ic50 1nM
MRCK: ic50 150nM
In Vitro
Chroman 1 also shows inhibitory activities against MRCK (IC50: 150nM). However, it has no effect on PKA (IC50, > 20000nM) or AKT1 (IC50, >20000nM).

Product Categories/Family for Chroman 1, inhibitor

Cell Cycle/Checkpoint; ROCK; Stem Cells

Structure of Chroman 1, inhibitor

Chroman 1 Inhibitor – Cat# MBS5754712

Product References and Citations for Chroman 1, inhibitor

Yen Ting Chen, et al. Asymmetric synthesis of potent chroman-based Rho kinase (ROCK-II) inhibitors. Med.Chem.Commun., 2011, 2, 73-75.
Yen Ting Chen, et al. Asymmetric synthesis of potent chroman-based Rho kinase (ROCK-II) inhibitors. Med.Chem.Commun., 2011, 2, 73-75.

Other Notes

Small volumes of Chroman 1, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000