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Clobetasone butyrate Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5754725

Clobetasone butyrate is a synthetic glucocorticoid. Clobetasone butyrate can be used to relieve corticosteroid-responsive dermatoses, including psoriasis and atopic dermatitis. It has topical anti-inflammatory activity, especially in the skin. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Clobetasone butyrate, Inhibitor
Full Product Name
Clobetasone butyrate
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
478.98
Solubility
DMSO: 250mg/mL (521.94mM)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C26H32ClFO5
SMILES
C[C@@]1(C2)[C@](C(CCl)=O)(OC(CCC)=O)[C@@H](C)C[C@@]1([H])[C@]3([H])CCC4=CC(C=C[C@]4(C)[C@@]3(F)C2=O)=O
CAS Number
25122-57-0
Target & IC50
glucocorticoid
In Vitro
Clobetasone butyrate (application on the skin; 0.05%; 7 weeks) causes epidermal thinning in the skin. Clobetasone butyrate causes much less epidermal thinning in the pig than flurandrenolone (0.05%) or fluocinolone acetonide (0.025%) [1].

Structure of Clobetasone butyrate, inhibitor

Clobetasone butyrate Inhibitor – Cat# MBS5754725

Product References and Citations for Clobetasone butyrate, inhibitor

Munro DD, et al. Clobetasone butyrate, a new topical corticosteroid: clinical activity and effects on pituitary-adrenal axis function and model of epidermal atrophy.
Munro DD, et al. Clobetasone butyrate, a new topical corticosteroid: clinical activity and effects on pituitary-adrenal axis function and model of epidermal atrophy.
Michael Stewart, et al. Clobetasone butyrate for inflammatory skin conditions.
Michael Stewart, et al. Clobetasone butyrate for inflammatory skin conditions.

Other Notes

Small volumes of Clobetasone butyrate, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Clobetasone butyrate purchase

MBS5754725 is an inhibitor targeting Clobetasone butyrate.
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