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CU-CPT22 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5754749

CU-CPT22 is an inhibitor of toll-like receptor 1 and 2 (TLR1/2) protein complex. It competes with the synthetic triacylated lipoprotein (Pam3CSK4) binding to TLR1/2 (Ki: 0.41uM). CU-CPT22 blocks Pam3CSK4-induced TLR1/2 activation (IC50: 0.58uM). More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CU-CPT22, Inhibitor
Full Product Name
CU-CPT22
Product Gene Name
CU-CPT22, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
362.37
Solubility
DMSO: 125mg/mL (344.95mM)
H2O: <0.1mg/mL (insoluble)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C19H22O7
SMILES
O=C(C(C=C1O)=CC2=CC(OC)=C(O)C(O)=C2C1=O)OCCCCCC
CAS Number
1416324-85-0
Target & IC50
TLR1/2: ic50 0.41uM (ki)

Structure of CU-CPT22, inhibitor

CU-CPT22 Inhibitor – Cat# MBS5754749

Product References and Citations for CU-CPT22, inhibitor

Cheng K, et al. Discovery of small-molecule inhibitors of the TLR1/TLR2 complex. Angew Chem Int Ed Engl. 2012 Dec 3;51(49):12246-9.
Cheng K, et al. Discovery of small-molecule inhibitors of the TLR1/TLR2 complex. Angew Chem Int Ed Engl. 2012 Dec 3;51(49):12246-9.

Other Notes

Small volumes of CU-CPT22, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CU-CPT22 purchase

MBS5754749 is an inhibitor targeting CU-CPT22.
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