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EN40 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5754828

EN40, as a covalent ligand, is a selective inhibitor of aldehyde dehydrogenase 3A1 (IC50: 2uM). More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
EN40, Inhibitor
Full Product Name
EN40
Product Gene Name
EN40, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
217.26
Solubility
DMSO: 5mg/mL (23.01mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C13H15NO2
SMILES
C=CC(N1CCC(C)=C(C2=CC=CO2)C1)=O
CAS Number
2094547-67-6
Target & IC50
ALDH3A1: ic50 2uM
In Vitro
EN40 (i.p.; 50mg/kg; from 14 days; once per day) displays strong anti-tumorigenic effects in established A549 tumor xenografts and it also shows good tolerability with no bodyweight loss in mice.

Structure of EN40, inhibitor

EN40 Inhibitor – Cat# MBS5754828

Product References and Citations for EN40, inhibitor

Counihan JL,et al.Chemoproteomics-Enabled Covalent Ligand Screening Reveals ALDH3A1 as a Lung Cancer Therapy Target. ACS Chem Biol. 2018 Aug 17;13(8):1970-1977
Counihan JL,et al.Chemoproteomics-Enabled Covalent Ligand Screening Reveals ALDH3A1 as a Lung Cancer Therapy Target. ACS Chem Biol. 2018 Aug 17;13(8):1970-1977

Other Notes

Small volumes of EN40, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for EN40 purchase

MBS5754828 is an inhibitor targeting EN40.
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