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EN460 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5754829

EN460 is an inhibitor of endoplasmic reticulum oxidation 1 (ERO1) and interacts selectively (IC50: 1.9 uM) with the reduced, active form of ERO1alpha and prevents its reoxidation. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
EN460, Inhibitor
Full Product Name
EN460
Product Gene Name
EN460, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
460.79
Solubility
DMSO: 12.5mg/mL (27.13mM) Need ultrasonic
H2O: <0.1mg/mL (insoluble)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C22H12ClF3N2O4
SMILES
FC(F)(F)C1=NN(C2=CC(C(O)=O)=C(Cl)C=C2)C(/C1=C\C3=CC=C(C4=CC=CC=C4)O3)=O
CAS Number
496807-64-8
Target & IC50
Others

Structure of EN460, inhibitor

EN460 Inhibitor – Cat# MBS5754829

Product References and Citations for EN460, inhibitor

Blais JD, et al. A small molecule inhibitor of endoplasmic reticulum oxidation 1 (ERO1) with selectively reversible thiol reactivity. J Biol Chem. 2010 Jul 2;285(27):20993-1003.
Blais JD, et al. A small molecule inhibitor of endoplasmic reticulum oxidation 1 (ERO1) with selectively reversible thiol reactivity. J Biol Chem. 2010 Jul 2;285(27):20993-1003.

Other Notes

Small volumes of EN460, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for EN460 purchase

MBS5754829 is an inhibitor targeting EN460.
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