ESI-05 Inhibitor

Name: ESI-05 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5754842
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5754842

ESI-05 is a specific EPAC2 (exchange protein directly activated by cAMP 2) antagonist (IC50: 0.4uM). ESI-05 inhibits cAMP-mediated activation of EPAC2, as well as EAPC2, mediated Rap1 activation. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ESI-05, Inhibitor

Full Product Name

ESI-05

Product Gene Name

ESI-05, inhibitor

Product Synonym Names

NSC 116966

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

274.38

Solubility

DMSO: 83.33mg/mL (303.70mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C16H18O2S

SMILES

O=S(C1=C(C)C=C(C)C=C1C)(C2=CC=C(C)C=C2)=O

CAS Number

5184-64-5

Target & IC50

EPAC2: ic50 0.4uM

Product Categories/Family for ESI-05, inhibitor

GPCR/G Protein; cAMP

Product References and Citations for ESI-05, inhibitor

Tsalkova T, et al. Isoform-specific antagonists of exchange proteins directly activated by cAMP. Proc Natl Acad Sci U S A. 2012 Nov 6;109(45):18613-8.
Tsalkova T, et al. Isoform-specific antagonists of exchange proteins directly activated by cAMP. Proc Natl Acad Sci U S A. 2012 Nov 6;109(45):18613-8.

Other Notes

Small volumes of ESI-05, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ESI-05 purchase

MBS5754842 is an inhibitor targeting ESI-05.