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Foropafant Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5754876

Foropafant is a competitive, selective, and orally active platelet-activating factor (PAF) receptor antagonist (Ki: 57 pM). Foropafant potently inhibits PAF-induced aggregation of rabbit and human platelets. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Foropafant, Inhibitor
Full Product Name
Foropafant
Product Synonym Names
SR27417
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
464.72
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C28H40N4S
SMILES
CC(C)C1=CC(C(C)C)=C(C2=CSC(=N2)N(CCN(C)C)CC2=CC=CN=C2)C(=C1)C(C)C
CAS Number
136468-36-5
Target & IC50
[3H]PAF binding: ic50 57pM (ki)

Structure of Foropafant, inhibitor

Foropafant Inhibitor – Cat# MBS5754876

Product References and Citations for Foropafant, inhibitor

Herbert JM, et al. Biochemical and pharmacological activities of SR 27417, a highly potent, long-acting platelet-activating factor receptor antagonist. J Pharmacol Exp Ther. 1991 Oct;259(1):44-51.
Herbert JM, et al. Biochemical and pharmacological activities of SR 27417, a highly potent, long-acting platelet-activating factor receptor antagonist. J Pharmacol Exp Ther. 1991 Oct;259(1):44-51.

Other Notes

Small volumes of Foropafant, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Foropafant purchase

MBS5754876 is an inhibitor targeting Foropafant.
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