Glycerol phenylbutyrate Inhibitor

Name: Glycerol phenylbutyrate Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5754905
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5754905

Glycerol phenylbutyrate (GPB) is a new generation ammonia scavenger drug and it also is a sigma-2 (sigma2) receptor ligand (pKi: 8.02). More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Glycerol phenylbutyrate, Inhibitor

Full Product Name

Glycerol phenylbutyrate

Product Synonym Names

HPN-100

Form/Format

Solid. Powder

Purity/Purification

99.74%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

530.65

Solubility

DMSO: 150mg/mL (282.67mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C33H38O6

SMILES

O=C(CCCC1=CC=CC=C1)OC(COC(CCCC2=CC=CC=C2)=O)COC(CCCC3=CC=CC=C3)=O

CAS Number

611168-24-2

Target & IC50

sigma2 receptor

In Vitro

Glycerol phenylbutyrate may have therapeutic potential in additional conditions such as chronic hepatic encephalopathy or other inherited metabolic disorders. Glycerol phenylbutyrate also has the potential for the treatment of hyperammonemia [1,2].

Product Categories/Family for Glycerol phenylbutyrate, inhibitor

GPCR/G Protein; Sigma receptor

Product References and Citations for Glycerol phenylbutyrate, inhibitor

Rescifina A, et al. Development of a Sigma-2 Receptor affinity filter through a Monte Carlo based QSAR analysis. Eur J Pharm Sci. 2017 Aug 30;106:94-101.
Rescifina A, et al. Development of a Sigma-2 Receptor affinity filter through a Monte Carlo based QSAR analysis. Eur J Pharm Sci. 2017 Aug 30;106:94-101.
Oishi K, et al. Glycerol phenylbutyrate for the chronic management of urea cycle disorders. Expert Rev Endocrinol Metab. 2014 Sep;9(5):427-434.
Oishi K, et al. Glycerol phenylbutyrate for the chronic management of urea cycle disorders. Expert Rev Endocrinol Metab. 2014 Sep;9(5):427-434.

Other Notes

Small volumes of Glycerol phenylbutyrate, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Glycerol phenylbutyrate purchase

MBS5754905 is an inhibitor targeting Glycerol phenylbutyrate.