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GSK2194069 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5754925

GSK2194069 is a specific inhibitor of the beta-ketoacyl reductase (KR) activity of hFAS (IC50: 7.7 +/- 4.1nM in an assay detecting released CoA). More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GSK2194069, Inhibitor
Full Product Name
GSK2194069
Product Gene Name
GSK2194069, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
428.48
Solubility
DMSO: 100mg/mL (233.38mM)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C25H24N4O3
SMILES
O=C(N1C[C@H](CC2=NNC(N2C3=CC=C(C4=CC=C(OC=C5)C5=C4)C=C3)=O)CC1)C6CC6
CAS Number
1332331-08-4
Target & IC50
Others

Structure of GSK2194069, inhibitor

GSK2194069 Inhibitor – Cat# MBS5754925

Product References and Citations for GSK2194069, inhibitor

Hardwicke MA, et al. A human fatty acid synthase inhibitor binds beta-ketoacyl reductase in the keto-substrate site. Nat Chem Biol. 2014 Sep;10(9):774-9.
Hardwicke MA, et al. A human fatty acid synthase inhibitor binds beta-ketoacyl reductase in the keto-substrate site. Nat Chem Biol. 2014 Sep;10(9):774-9.

Other Notes

Small volumes of GSK2194069, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GSK2194069 purchase

MBS5754925 is an inhibitor targeting GSK2194069.
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