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HJC0197 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5754962

HJC0197 selectively blocks cAMP-induced Epac activation. HJC0197 is an effective exchange protein. Which straightly activated by cAMP (Epac) antagonist (IC50=5.9 uM for Epac2). More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
HJC0197, Inhibitor
Full Product Name
HJC0197
Product Gene Name
HJC0197, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
339.45
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C19H21N3OS
SMILES
Cc1ccc(C)c(CSc2nc(C3CCCC3)c(C#N)c(=O)[nH]2)c1
CAS Number
1383539-73-8
Target & IC50
Others
Epac1
Epac2

Structure of HJC0197, inhibitor

HJC0197 Inhibitor – Cat# MBS5754962

Product References and Citations for HJC0197, inhibitor

Chen H, et al. 5-Cyano-6-oxo-1,6-dihydro-pyrimidines as potent antagonists targeting exchange proteins directly activated by cAMP. Bioorg Med Chem Lett. 2012 Jun 15;22(12):4038-43.
Chen H, et al. 5-Cyano-6-oxo-1,6-dihydro-pyrimidines as potent antagonists targeting exchange proteins directly activated by cAMP. Bioorg Med Chem Lett. 2012 Jun 15;22(12):4038-43.

Other Notes

Small volumes of HJC0197, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HJC0197 purchase

MBS5754962 is an inhibitor targeting HJC0197.
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