• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

TBK1/IKKepsilon-IN-2 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5754985

MBS5754985 is an inhibitor targeting TBK1/IKKepsilon-IN-2. TBK1/IKKepsilon-IN-2 is a dual inhibitor of TBK1 and IKKepsilon. More details

Please Inquire
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TBK1/IKKepsilon-IN-2, Inhibitor
Full Product Name
TBK1/IKKepsilon-IN-2
Product Gene Name
TBK1/IKKepsilon-IN-2, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.77%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
457.52
Solubility
DMSO: 16.5mg/ml (36.06mM) Need ultrasonic and warming
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C26H27N5O3
SMILES
N#CC1=C(OC2CCOCC2)C=CC(=C1)C1=NC(NC2=CC=C(C=C2)N2CCOCC2)=NC=C1
CAS Number
1292310-49-6
Target & IC50
TBK1: ic50 0.6nM (at 5uM ATP)
IKKepsilon: ic50 3.9nM (at 10uM ATP)

Product Categories/Family for TBK1/IKKepsilon-IN-2, inhibitor

NF-kappab; IkappaB/IKK

Structure of TBK1/IKKepsilon-IN-2, inhibitor

TBK1/IKKepsilon-IN-2 Inhibitor – Cat# MBS5754985

Product References and Citations for TBK1/IKKepsilon-IN-2, inhibitor

Muvaffak A, et al. Evaluating TBK1 as a therapeutic target in cancers with activated IRFMol Cancer Res. 2014 Jul;12(7):1055-66.

Other Notes

Small volumes of TBK1/IKKepsilon-IN-2, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000