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Imanixil Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5754987

Imanixil is an inducer of the LDL receptor (LDLR) and it is also a potent cholesterol-lowering compound. It also inhibits very low density-lipoprotein (VLDL) production and consequently decreases atherosclerosis development. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Imanixil, Inhibitor
Full Product Name
Imanixil
Product Synonym Names
HOE-402(free base)
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
394.35
Solubility
DMSO: 300mg/mL (760.75mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C17H17F3N6O2
SMILES
O=C(C1=CN=C(N2CC(C)(C)NC2=O)N=C1N)NC3=CC=CC(C(F)(F)F)=C3
CAS Number
75689-93-9
Target & IC50
Others

Structure of Imanixil, inhibitor

Imanixil Inhibitor – Cat# MBS5754987

Product References and Citations for Imanixil, inhibitor

Draijer R, et al. HOE 402 lowers serum cholesterol levels by reducing VLDL-lipid production, and not by induction of the LDL receptor, and reduces atherosclerosis in wild-type and LDL receptor-deficient mice. Biochem Pharmacol. 2002 May 1;63(9):1755-61.
Draijer R, et al. HOE 402 lowers serum cholesterol levels by reducing VLDL-lipid production, and not by induction of the LDL receptor, and reduces atherosclerosis in wild-type and LDL receptor-deficient mice. Biochem Pharmacol. 2002 May 1;63(9):1755-61.

Other Notes

Small volumes of Imanixil, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Imanixil purchase

MBS5754987 is an inhibitor targeting Imanixil.
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