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Imirestat Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5754990

Imirestat is an aldose reductase inhibitor. It is used for the treatment,of diabetes. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Imirestat, Inhibitor
Full Product Name
Imirestat
Product Synonym Names
AL 1576; Alcon 1576; HOE 843
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
286.23
Solubility
DMSO: 250mg/mL (873.42mM)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C15H8F2N2O2
SMILES
O=C1NC2(C(N1)=O)C3=C(C4=C2C=C(F)C=C4)C=CC(F)=C3
CAS Number
89391-50-4
Target & IC50
Others
In Vitro
Imirestat (1mg/kg) improves nerve conduction velocity. However, it is without effect upon the resistance to hypoxic conduction blockade or the deficit in insulin-stimulated oubain-sensitive ATPase activity[1].

Structure of Imirestat, inhibitor

Imirestat Inhibitor – Cat# MBS5754990

Product References and Citations for Imirestat, inhibitor

Carrington AL, et al. Aldose reductase inhibition with imirestat-effects on impulse conduction and insulin-stimulation of Na+/K(+)-adenosine triphosphatase activity in sciatic nerves of streptozotocin-diabetic rats. Diabetologia. 1991 Jun;34(6):397-401.
Carrington AL, et al. Aldose reductase inhibition with imirestat-effects on impulse conduction and insulin-stimulation of Na+/K(+)-adenosine triphosphatase activity in sciatic nerves of streptozotocin-diabetic rats. Diabetologia. 1991 Jun;34(6):397-401.

Other Notes

Small volumes of Imirestat, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Imirestat purchase

MBS5754990 is an inhibitor targeting Imirestat.
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