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inS3-54A18 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5755000

MBS5755000 is an inhibitor targeting inS3-54A18. inS3-54A18 is a potent inhibitor of STAT3. It has anti-cancer properties. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
inS3-54A18, Inhibitor
Full Product Name
inS3-54A18
Product Gene Name
inS3-54A18, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
373.83
Solubility
DMSO: 150mg/mL (401.25mM)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C23H16ClNO2
SMILES
O=C1N(C2=CC=C(O)C=C2)C(C3=CC=CC=C3)=C/C1=C/C4=CC=C(Cl)C=C4
CAS Number
328998-53-4
Target & IC50
STAT3

Product Categories/Family for inS3-54A18, inhibitor

JAK/STAT signaling; STAT; Stem Cells

Structure of inS3-54A18, inhibitor

inS3-54A18 Inhibitor – Cat# MBS5755000

Product References and Citations for inS3-54A18, inhibitor

Huang W, et al. Small-molecule inhibitors targeting the DNA-binding domain of STAT3 suppress tumor growth, metastasis and STAT3 target gene expression in vivo. Oncogene. 2016 Feb 11;35(6):783-92
Huang W, et al. Small-molecule inhibitors targeting the DNA-binding domain of STAT3 suppress tumor growth, metastasis and STAT3 target gene expression in vivo. Oncogene. 2016 Feb 11;35(6):783-92

Other Notes

Small volumes of inS3-54A18, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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