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Integrin Antagonists 27 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5755002

Integrin Antagonists 27 is a small molecule integrin alphavbeta3 antagonist. It has a binding affinity of 18nM and as a novel anticancer agent. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Integrin Antagonists 27, Inhibitor
Full Product Name
Integrin Antagonists 27
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
444.44
Solubility
DMSO: 100mg/mL (225.00mM)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C24H20N4O5
SMILES
O=C(O)C1=CC=CC(N2C(/C=C(C(N3CC(NC4=CC=C(C)C=C4)=O)=O)\NC3=O)=CC=C2)=C1
CAS Number
593274-97-6
Target & IC50
Others
In Vitro
Integrin Antagonists 27 is treated with a panel of cancer cell lines. Which include breast cancer cell line MDA-MB-435, breast cancer cell lines MCF-7, mouse fibroblast NIH3T3, ovarian cancer cell line HEY, lung cancer cell line NCI-H1975. It has an IC50 of >20uM.

Structure of Integrin Antagonists 27, inhibitor

Integrin Antagonists 27 Inhibitor – Cat# MBS5755002

Product References and Citations for Integrin Antagonists 27, inhibitor

Dayam R, et al. Discovery of small molecule integrin alphavbeta3 antagonists as novel anticancer agents. J Med Chem. 2006 Jul 27;49(15):4526-4534.
Dayam R, et al. Discovery of small molecule integrin alphavbeta3 antagonists as novel anticancer agents. J Med Chem. 2006 Jul 27;49(15):4526-4534.

Other Notes

Small volumes of Integrin Antagonists 27, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Integrin Antagonists 27 purchase

MBS5755002 is an inhibitor targeting Integrin Antagonists 27.
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