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KT185 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5755052

KT185 is an orally-bioavailable and brain-penetrant ABHD6 inhibitor (IC50: 0.21nM in Neuro2A cells). More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
KT185, Inhibitor
Full Product Name
KT185
Product Gene Name
KT185, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
519.64
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C32H33N5O2
SMILES
O=C(N1N=NC(C2=CC=C(C=C2)C3=CC=CC(C(N4CCCCC4)=O)=C3)=C1)N5C(CCCC5)C6=CC=CC=C6
CAS Number
1472640-86-0
Target & IC50
ABHD6: ic50 0.21nM

Structure of KT185, inhibitor

KT185 Inhibitor – Cat# MBS5755052

Product References and Citations for KT185, inhibitor

Hsu KL, et al. Discovery and optimization of piperidyl-1,2,3-triazole ureas as potent, selective, and in vivo-active inhibitors of alpha/beta-hydrolase domain containing 6 (ABHD6). J Med Chem. 2013 Nov 14;56(21):8270-9.
Hsu KL, et al. Discovery and optimization of piperidyl-1,2,3-triazole ureas as potent, selective, and in vivo-active inhibitors of alpha/beta-hydrolase domain containing 6 (ABHD6). J Med Chem. 2013 Nov 14;56(21):8270-9.

Other Notes

Small volumes of KT185, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KT185 purchase

MBS5755052 is an inhibitor targeting KT185.
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