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KY1220 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5755056

KY1220 destabilizes both beta-catenin and Ras by targeting the Wnt/beta-catenin pathway. It has an IC50 of 2.1uM in HEK293 reporter cells. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
KY1220, Inhibitor
Full Product Name
KY1220
Product Gene Name
KY1220, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
314.32
Solubility
DMSO: 100mg/mL (318.15mM)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C14H10N4O3S
SMILES
O=C(/C(N1)=C/C2=CC=CN2C3=CC=C([N+]([O-])=O)C=C3)NC1=S
CAS Number
292168-79-7
Target & IC50
HEK293 reporter cells: ic50 2.1uM

Structure of KY1220, inhibitor

KY1220 Inhibitor – Cat# MBS5755056

Product References and Citations for KY1220, inhibitor

Cha PH, et al. Small-molecule binding of the axin RGS domain promotes beta-catenin and Ras degradation. Nat Chem Biol. 2016 Aug;12(8):593-600.
Cha PH, et al. Small-molecule binding of the axin RGS domain promotes beta-catenin and Ras degradation. Nat Chem Biol. 2016 Aug;12(8):593-600.

Other Notes

Small volumes of KY1220, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KY1220 purchase

MBS5755056 is an inhibitor targeting KY1220.
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