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LP-533401 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5755114

LP-533401 is an inhibitor of Tryptophan hydroxylase 1. It is used for regulates serotonin production in the gut. More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
LP-533401, Inhibitor
Full Product Name
LP-533401
Product Gene Name
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
526.48
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C27H22F4N4O3
SMILES
N[C@@H](CC1=CC=C(C2=NC(N)=NC(OC(C3=CC=C(C4=CC=CC(F)=C4)C=C3)C(F)(F)F)=C2)C=C1)C(O)=O
CAS Number
945976-43-2
Target & IC50
Tryptophan hydroxylase

Product Categories/Family for LP-533401, inhibitor

Structure of LP-533401, inhibitor

LP-533401 Inhibitor – Cat# MBS5755114

Product References and Citations for LP-533401, inhibitor

Yadav, V.K., et al. Inhibition of gut-derived serotonin synthesis: A potential bone anabolic treatment, Nat. Med. 16(3), 308-312 (2010).
Yadav, V.K., et al. Inhibition of gut-derived serotonin synthesis: A potential bone anabolic treatment, Nat. Med. 16(3), 308-312 (2010).
Abid S, et al. Inhibition of gut- and lung-derived serotonin attenuates pulmonary hypertension in mice. Am J Physiol Lung Cell Mol Physiol. 2012 Sep 15;303(6):L500-8.
Abid S, et al. Inhibition of gut- and lung-derived serotonin attenuates pulmonary hypertension in mice. Am J Physiol Lung Cell Mol Physiol. 2012 Sep 15;303(6):L500-8.
Krevvata M, et al. Inhibition of leukemia cell engraftment and disease progression in mice by osteoblasts. Blood. 2014 Oct 30;124(18):2834-46.
Krevvata M, et al. Inhibition of leukemia cell engraftment and disease progression in mice by osteoblasts. Blood. 2014 Oct 30;124(18):2834-46.

Other Notes

Small volumes of LP-533401, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LP-533401 purchase

MBS5755114 is an inhibitor targeting LP-533401.
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