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MA-2029 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5755155

MA-2029 is selective for the motilin receptor over various other receptors and ion channels. MA-2029 is a selective and competitive motilin receptor antagonist (IC50=4.9nM). MA-2029 may be useful for gastrointestinal disorders associated with disturbed… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MA-2029, Inhibitor
Full Product Name
MA-2029
Product Gene Name
MA-2029, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
556.71
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C31H45FN4O4
SMILES
FC(C=C1)=CC=C1C[C@H](NC)C(N(C)[C@@H](C(C)C)C(N[C@H](C(NCC)=O)CC2=CC(C(C)(C)C)=C(O)C=C2)=O)=O
CAS Number
287206-61-5
Target & IC50
motilin receptor: ic50 4.9nM
In Vitro
MA-2029 (10mg/kg; p.o.) treatment,displays that the t1/2 is 2 hours. The inhibition is significant at 30 min after administration of 3mg/kg or more and at 4 hours after administration of 10mg/kg or more (MA-2029), so the administration of 10mg/kg or more causes inhibitory effects from 30 min or less to at least 4 hours after administration. MA-2029 (0.3-3mg/kg; p.o.) dose-dependently suppresses the number of abdominal muscle contractions induced under the same conditions and cause significant inhibition at 3mg/kg.

Structure of MA-2029, inhibitor

MA-2029 Inhibitor – Cat# MBS5755155

Product References and Citations for MA-2029, inhibitor

Sudo H, et al. Oral administration of MA-2029, a novel selective and competitive motilin receptor antagonist, inhibits motilin-induced intestinal contractions and visceral pain in rabbits. Eur J Pharmacol. 2008 Mar 10;581(3):296-305.

Other Notes

Small volumes of MA-2029, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MA-2029 purchase

MBS5755155 is an inhibitor targeting MA-2029.
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