Mal-amido-PEG4-NHS ester Inhibitor

Name: Mal-amido-PEG4-NHS ester Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5755158
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5755158

Mal-amido-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Mal-amido-PEG4-NHS ester, Inhibitor

Full Product Name

Mal-amido-PEG4-NHS ester

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

513.50

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C22H31N3O11

SMILES

O=C(CCN1C(=O)C=CC1=O)NCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O

CAS Number

756525-99-2

Target & IC50

PEGs
Alkyl/ether

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Product Categories/Family for Mal-amido-PEG4-NHS ester, inhibitor

PROTAC

Product References and Citations for Mal-amido-PEG4-NHS ester, inhibitor

An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.
An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Other Notes

Small volumes of Mal-amido-PEG4-NHS ester, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Mal-amido-PEG4-NHS ester purchase

MBS5755158 is an inhibitor targeting Mal-amido-PEG4-NHS ester.