• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

MF498 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5755183

MF498 is a novel and selective E prostanoid receptor 4 (EP4 receptor) antagonist, displayed a strong binding affinity for the EP4 receptor (Ki: 0.7nM). More details

Please Inquire
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MF498, Inhibitor
Full Product Name
MF498
Product Gene Name
MF498, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
603.69
Solubility
DMSO: 31mg/mL (51.35mM)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C32H33N3O7S
SMILES
O=C1N(C2=C(C)C=C(CS(NC(CC3=CC=CC=C3OC)=O)(=O)=O)C=C2)CC4=C(OCC)C5=NC=CC=C5C(OCC)=C41
CAS Number
915191-42-3
Target & IC50
Others
In Vitro
MF498 on inflammation in adjuvant-caused arthritis (AIA), a rat model for rheumatoid arthritis (RA), and joint pain in a guinea pig model of iodoacetate-induced osteoarthritis (OA). MF498 relieves joint inflammation and pain in rodent models of rheumatoid and osteoarthritis.

Structure of MF498, inhibitor

MF498 Inhibitor – Cat# MBS5755183

Product References and Citations for MF498, inhibitor

Clark P, et al. MF498 [N-{[4-(5,9-Diethoxy-6-oxo-6,8-dihydro-7H-pyrrolo[3,4-g]quinolin-7-yl)-3-methylbenzyl]sulfonyl}-2-(2-methoxyphenyl)acetamide], a selective E prostanoid receptor 4 antagonist, relieves joint inflammation and pain in rodent models of rheumatoid and osteoarthritis. J Pharmacol Exp Ther. 2008 May;325(2):425-434.

Other Notes

Small volumes of MF498, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MF498 purchase

MBS5755183 is an inhibitor targeting MF498.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000