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ML132 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5755206

MBS5755206 is an inhibitor targeting ML132. ML132 is an effective and selective inhibitor of caspase 1 (IC50: 0.316nM). More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ML132, Inhibitor
Full Product Name
ML132
Product Gene Name
ML132, inhibitor
Product Synonym Names
NCGC 00185682
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
477.94
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C22H28ClN5O5
SMILES
ClC1=CC(C(N[C@@H](C(C)(C)C)C(N2CCC[C@H]2C(N[C@@H](CC(O)=O)C#N)=O)=O)=O)=CC=C1N
CAS Number
1230628-71-3
Target & IC50
Caspase 1: ic50 0.316nM

Structure of ML132, inhibitor

ML132 Inhibitor – Cat# MBS5755206

Product References and Citations for ML132, inhibitor

Boxer MB, et al. A highly potent and selective caspase 1 inhibitor that utilizes a key 3-cyanopropanoic acid moiety. ChemMedChem. 2010 May 3;5(5):730-8.

Other Notes

Small volumes of ML132, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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