ML418 Inhibitor

Name: ML418 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5755211
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5755211

ML418 is a potent, selective and CNS penetrating Kir7.1 potassium channel blocker (IC50 = 310nM), and also potently inhibits Kir6.2/SUR1. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ML418, Inhibitor

Full Product Name

ML418

Product Gene Name

ML418, inhibitor

Form/Format

Solid. Powder

Purity/Purification

98.10%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

377.87

Solubility

DMSO: 20mg/mL (52.93mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C19H24ClN3O3

SMILES

CC(C)OC(=O)NC1CCN(Cc2cc(Cl)c3cccnc3c2O)CC1

CAS Number

1928763-08-9

Target & IC50

Others
Kir7.1

Product Categories/Family for ML418, inhibitor

Membrane transporter/Ion channel

Product References and Citations for ML418, inhibitor

ML418, et al. ML418: The First Selective, Sub-Micromolar Pore Blocker of Kir7.1 Potassium Channels. ACS Chem Neurosci. 2016 Jul 20;7(7):1013-23.

Other Notes

Small volumes of ML418, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ML418 purchase

MBS5755211 is an inhibitor targeting ML418.