• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

MPS1-IN-3 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5755224

MBS5755224 is an inhibitor targeting Mps1-IN-3. Mps1-IN-3 is an effective and selective inhibitor of MPS1 kinase (IC50: 50nM). More details

Please Inquire
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Mps1-IN-3, Inhibitor
Full Product Name
Mps1-IN-3
Product Gene Name
Mps1-IN-3, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
537.63
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C26H31N7O4S
SMILES
O=S(C1=C(NC2=NC(NC3=CC=C(N4CCC(O)CC4)C=C3OC)=NC5=C2N=CN5)C=CC=C1)(C(C)C)=O
CAS Number
1609584-72-6
Target & IC50
Mps1: ic50 50nM
In Vitro
Mps1-IN-3 (2mg/kg, i.v.) sensitizes glioblastoma cells in murine tumor models. It has prolonged survival and no toxicity.

Product Categories/Family for Mps1-IN-3, inhibitor

Ubiquitination; E1/E2/E3 Enzyme; Cytoskeletal Signaling

Structure of Mps1-IN-3, inhibitor

MPS1-IN-3 Inhibitor – Cat# MBS5755224

Product References and Citations for Mps1-IN-3, inhibitor

Tannous BA, et al. Effects of the selective MPS1 inhibitor MPS1-IN-3 on glioblastoma sensitivity to antimitotic drugs. J Natl Cancer Inst. 2013 Sep 4;105(17):1322-31.

Other Notes

Small volumes of Mps1-IN-3, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000