MS4078 Inhibitor

Name: MS4078 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5755232
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5755232

MS4078 is an anaplastic lymphoma kinase (ALK) PROTAC. It has a Kd of 19nM for binding affinity to ALK. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

MS4078, Inhibitor

Full Product Name

MS4078

Product Gene Name

MS4078, inhibitor

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

914.47

Solubility

DMSO: 250mg/mL (273.38mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C45H52ClN9O8S

SMILES

CC(C)S(C1=C(NC2=NC(NC3=C(OC(C)C)C=C(C4CCN(CC(NCCNC5=C(C(N(C6C(NC(CC6)=O)=O)C7=O)=O)C7=CC=C5)=O)CC4)C(C)=C3)=NC=C2Cl)C=CC=C1)(=O)=O

CAS Number

2229036-62-6

Target & IC50

ALK
Cereblon

Product Categories/Family for MS4078, inhibitor

Chromatin/Epigenetic; HDAC; Angiogenesis; Tyrosine Kinase/Adaptors

Product References and Citations for MS4078, inhibitor

Zhang C, et al. Proteolysis Targeting Chimeras (PROTACs) of Anaplastic Lymphoma Kinase (ALK). Eur J Med Chem. 2018 May 10;151:304-314.

Other Notes

Small volumes of MS4078, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MS4078 purchase

MBS5755232 is an inhibitor targeting MS4078.