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Nemorexant Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5755255

Nemorexant is an effective orexin receptor antagonist. It also has IC50s of 2nM and 3nM for the Ox1 receptor and Ox2 receptor, respectively. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Nemorexant, Inhibitor
Full Product Name
Nemorexant
Product Synonym Names
ACT-541468
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
450.92
Solubility
DMSO: 250mg/mL (554.42mM)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C23H23ClN6O2
SMILES
C[C@](CCC1)(C2=NC3=CC=C(Cl)C(C)=C3N2)N1C(C4=C(N5N=CC=N5)C=CC(OC)=C4)=O
CAS Number
1505484-82-1
Target & IC50
Ox1 receptor: ic50 2nM
Ox2 receptor: ic50 3nM

Product References and Citations for Nemorexant, inhibitor

BOSS, Christoph, et al. USE OF BENZIMIDAZOLE-PROLINE DERIVATIVES. WO2015083094A1.

Other Notes

Small volumes of Nemorexant, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Nemorexant purchase

MBS5755255 is an inhibitor targeting Nemorexant.
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