NKH477 Inhibitor

Name: NKH477 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5755269
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5755269

NKH477 is a novel water-soluble forskolin derivative that improves cardiac failure mainly through its beneficial effects on diastolic cardiac function. NKH477 shows an antiproliferative effect in vivo with an altered cytokine profile to inhibit the acute… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

NKH477, Inhibitor

Full Product Name

NKH477

Product Gene Name

NKH477, inhibitor

Product Synonym Names

Colforsin dapropate hydrochloride

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

546.09

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C27H44ClNO8

SMILES

O[C@@]12[C@@]3([C@@](C(C)(CC[C@@H]3O)C)([H])[C@H](OC(CCN(C)C)=O)[C@H](OC(C)=O)[C@]1(O[C@](C=C)(C)CC2=O)C)C.Cl

CAS Number

138605-00-2

Target & IC50

Adenylate Cyclase

In Vitro

NKH477 (p.o.; 1-3mg/kg/day; days 3 and 5) prolonged lung allograft survival in a dose dependent manner.

Product Categories/Family for NKH477, inhibitor

Neuroscience; nMDAR

Product References and Citations for NKH477, inhibitor

Nakashima S, et al. Antiproliferative effects of NKH477, a forskolin derivative, on cytokine profile in rat lung allografts. J Heart Lung Transplant. 2005 Apr;24(4):462-9.

Other Notes

Small volumes of NKH477, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NKH477 purchase

MBS5755269 is an inhibitor targeting NKH477.