NRC-2694 Inhibitor

Name: NRC-2694 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5755275
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5755275

NRC-2694 is an antagonist of the epidermal growth factor receptor (EGFR). It has anti-cancer and anti-proliferative properties. More details

Please Inquire

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

NRC-2694, Inhibitor

Full Product Name

NRC-2694

Product Gene Name

NRC-2694, inhibitor

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

418.49

Solubility

DMSO: 250mg/mL (597.39mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C24H26N4O3

SMILES

COC1=CC2=NC=NC(NC3=CC=CC(C#C)=C3)=C2C=C1OCCCN4CCOCC4

CAS Number

936446-61-6

Target & IC50

EGFR

In Vitro

NRC-2694 (10mg/kg) regresses the tumor in mice. The maximum tolerated dose of NRC-2694 in male and female mice is 2000mg/kg (p.o.), in toxicity studies.

Product Categories/Family for NRC-2694, inhibitor

Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors

Product References and Citations for NRC-2694, inhibitor

Ramanadham Jyothi Prasad, et al. 6-7,dialkoxy quinazoline derivatives useful for treatment,of cancer related disorders. US 8143250 B2

Other Notes

Small volumes of NRC-2694, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NRC-2694 purchase

MBS5755275 is an inhibitor targeting NRC-2694.