NS13001 Inhibitor

Name: NS13001 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5755277
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5755277

NS13001 is a potent, selective, orally active allosteric positive modulator of SK channels (small conductance calcium-activated potassium channels). The EC50s are 1.8 and 0.14uM for SK2 and SK3, respectively. NS13001 holds promise as a potential therapeutic… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

NS13001, Inhibitor

Full Product Name

NS13001

Product Gene Name

NS13001, inhibitor

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

353.81

Solubility

DMSO: 100mg/mL (282.64mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C17H16ClN7

SMILES

CN1C=NC2=C(NC3=CC=C(Cl)C=C3)N=C(N4N=C(C)C=C4C)N=C12

CAS Number

1063331-94-1

Target & IC50

SK2: ic50 1.8uM (EC50)
SK3: ic50 0.14uM (EC50)

Product Categories/Family for NS13001, inhibitor

Cell Cycle/Checkpoint; CDK; Others

Product References and Citations for NS13001, inhibitor

Kasumu AW, et al. Selective positive modulator of calcium-activated potassium channels exerts beneficial effects in a mouse model of spinocerebellar ataxia type Chem Biol. 2012 Oct 26;19(10):1340-53.

Other Notes

Small volumes of NS13001, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NS13001 purchase

MBS5755277 is an inhibitor targeting NS13001.