NSC16168 Inhibitor

Name: NSC16168 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5755283
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5755283

NSC16168 inhibits DNA repair and potentiates CDDP efficacy in cancer. NSC16168 is a specific ERCC1-XPF inhibitor (IC50: 0.42uM). More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

NSC16168, Inhibitor

Full Product Name

NSC16168

Product Gene Name

NSC16168, inhibitor

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

473.5

Solubility

DMSO: 31.25mg/mL (66.00mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C17H15NO9S3

SMILES

NC1=C2C(C=C(S(=O)(O)=O)C=C2OS(C3=CC=C(C)C=C3)(=O)=O)=CC(S(O)(=O)=O)=C1

CAS Number

6837-93-0

Target & IC50

ERCC1-XPF: ic50 0.42uM

Product Categories/Family for NSC16168, inhibitor

Endocrinology/Hormones; Estrogen/progestogen Receptor; Others

Product References and Citations for NSC16168, inhibitor

Arora S, et al. Identification of small molecule inhibitors of ERCC1-XPF that inhibit DNA repair and potentiate cisplatin efficacy in cancer cells. Oncotarget. 2016 Nov 15;7(46):75104-75117.

Other Notes

Small volumes of NSC16168, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NSC16168 purchase

MBS5755283 is an inhibitor targeting NSC16168.