Ogerin Inhibitor

Name: Ogerin Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5755298
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5755298

Ogerin is a selective GPR68 positive allosteric modulator (pEC50: 6.83). Ogerin blocks recall in fear conditioning in mice. Ogerin displays inverse agonist and antagonist activity (Ki, 220nM) at A2A receptor and weak antagonist activity (Ki, 736nM) at 5-HT2B… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Ogerin, Inhibitor

Full Product Name

Ogerin

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

307.35

Solubility

DMSO: 250mg/mL (813.40mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C17H17N5O

SMILES

OCC1=C(C2=NC(N)=NC(NCC3=CC=CC=C3)=N2)C=CC=C1

CAS Number

1309198-71-7

Target & IC50

GPR68: ic50 6.83 (pEC50)
A2A receptoor: ic50 220nM (ki)
5-HT2B receptor: ic50 736nM

Product Categories/Family for Ogerin, inhibitor

Endocrinology/Hormones; GPCR/G Protein

Product References and Citations for Ogerin, inhibitor

Huang XP, et al. Allosteric ligands for the pharmacologically dark receptors GPR68 and GPR65. Nature. 2015 Nov 26;527(7579):477-83.
Huang XP, et al. Allosteric ligands for the pharmacologically dark receptors GPR68 and GPR65. Nature. 2015 Nov 26;527(7579):477-83.

Other Notes

Small volumes of Ogerin, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Ogerin purchase

MBS5755298 is an inhibitor targeting Ogerin.