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PCO371 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5755335

PCO371 is an orally active full agonist of parathyroid hormone receptor 1. It has no effect on PTH type 2 receptor. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PCO371, Inhibitor
Full Product Name
PCO371
Product Gene Name
PCO371, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
635.65
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C29H32F3N5O6S
SMILES
FC(F)(F)OC1=CC=C(C2=NC3(CCN(S(CCC4=C(C)C=C(N5C(NC(C5(C)C)=O)=O)C=C4C)(=O)=O)CC3)C(N2)=O)C=C1
CAS Number
1613373-33-3
Target & IC50
PTHR1

Structure of PCO371, inhibitor

PCO371 Inhibitor – Cat# MBS5755335

Product References and Citations for PCO371, inhibitor

Tamura T, et al. Identification of an orally active small-molecule PTHR1 agonist for the treatment,of hypoparathyroidism. Nat Commun. 2016 Nov 18;7:13384.
Tamura T, et al. Identification of an orally active small-molecule PTHR1 agonist for the treatment,of hypoparathyroidism. Nat Commun. 2016 Nov 18;7:13384.

Other Notes

Small volumes of PCO371, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PCO371 purchase

MBS5755335 is an inhibitor targeting PCO371.
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