PF-4191834 Inhibitor

Name: PF-4191834 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5755360
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5755360

PF-4191834 is an orally active, noniron chelating, and non-redox inhibitor of the 5-Lipoxygenase (5-LOX) (IC50=229nM). PF-4191834 shows ~300-fold selectivity for 5-LOX over 12-LOX and 15-LOX and displays no activity toward the cyclooxygenase enzymes.… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PF-4191834, Inhibitor

Full Product Name

PF-4191834

Product Gene Name

PF-4191834, inhibitor

Product Synonym Names

PF-04191834

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

393.5

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C22H23N3O2S

SMILES

O=C(C1(C2=CC=CC(SC3=CC=C(C4=CC=NN4C)C=C3)=C2)CCOCC1)N

CAS Number

1029317-21-2

Target & IC50

5-LOX

Product Categories/Family for PF-4191834, inhibitor

Metabolism; Lipoxygenase

Product References and Citations for PF-4191834, inhibitor

Masferrer JL, et al. Pharmacology of PF-4191834, a novel, selective non-redox 5-lipoxygenase inhibitor effective in inflammation and pain. J Pharmacol Exp Ther. 2010 Jul;334(1):294-301.
Masferrer JL, et al. Pharmacology of PF-4191834, a novel, selective non-redox 5-lipoxygenase inhibitor effective in inflammation and pain. J Pharmacol Exp Ther. 2010 Jul;334(1):294-301.

Other Notes

Small volumes of PF-4191834, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PF-4191834 purchase

MBS5755360 is an inhibitor targeting PF-4191834.