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PKR-IN-C16 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5755392

PKR-IN-C16 is a specific protein kinase (PKR) inhibitor. PKR-IN-C16 is able to inhibit the autophosphorylation of PKR and unlock the translation blockade induced by PKR in primary neuronal cultures.PKR-IN-C16 binds the ATP-binding site of PKR and blocks… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PKR-IN-C16, Inhibitor
Full Product Name
PKR-IN-C16
Product Gene Name
PKR-IN-C16, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
268.29
Solubility
DMSO: 15.67mg/mL (58.41mM)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C13H8N4OS
SMILES
O=C1Nc2ccc3ncsc3c2\C1=C\c1cnc[nH]1
CAS Number
608512-97-6
Target & IC50
Others

Structure of PKR-IN-C16, inhibitor

PKR-IN-C16 Inhibitor – Cat# MBS5755392

Product References and Citations for PKR-IN-C16, inhibitor

Tronel C, et al. The specific PKR inhibitor C16 prevents apoptosis and IL-1beta production in an acute excitotoxic rat model with a neuroinflammatory component. Neurochem Int. 2014 Jan;64:73-83.
Tronel C, et al. The specific PKR inhibitor C16 prevents apoptosis and IL-1beta production in an acute excitotoxic rat model with a neuroinflammatory component. Neurochem Int. 2014 Jan;64:73-83.

Other Notes

Small volumes of PKR-IN-C16, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PKR-IN-C16 purchase

MBS5755392 is an inhibitor targeting PKR-IN-C16.
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