PTI-428 Inhibitor

Name: PTI-428 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5755418
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5755418

PTI-428 is a specific amplifier of the cystic fibrosis transmembrane conductance regulator. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PTI-428, Inhibitor

Full Product Name

PTI-428

Product Gene Name

PTI-428, inhibitor

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

354.36

Solubility

DMSO: 250mg/mL (705.50mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C18H18N4O4

SMILES

O=C(C1=CC(C2=CC=CC=C2)=NO1)N[C@H]3C[C@H](C4=NN=C([C@H](O)C)O4)C3

CAS Number

1953130-87-4

Target & IC50

CFTR

Product Categories/Family for PTI-428, inhibitor

Membrane transporter/Ion channel; CFTR

Product References and Citations for PTI-428, inhibitor

Mijnders M, et al. Correcting CFTR folding defects by small-molecule correctors to cure cystic fibrosis. Curr Opin Pharmacol. 2017 Jun;34:83-90.
Mijnders M, et al. Correcting CFTR folding defects by small-molecule correctors to cure cystic fibrosis. Curr Opin Pharmacol. 2017 Jun;34:83-90.

Other Notes

Small volumes of PTI-428, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PTI-428 purchase

MBS5755418 is an inhibitor targeting PTI-428.