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Rhodamine 6G Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5755452

Rhodamine 6G is a rhodamine analog useful in Pgp efflux assays. It can be used in characterizing the kinetics of MRP1- mediated efflux as a laser dye and potential mitochondrial probe. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Rhodamine 6G, Inhibitor
Full Product Name
Rhodamine 6G
Product Synonym Names
Basic Red 1
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
479.01
Solubility
DMSO: 25mg/mL (52.19mM) Need ultrasonic
H2O: <0.1mg/mL (insoluble)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C28H31ClN2O3
SMILES
CC1=CC2=C(C3=CC=CC=C3C(OCC)=O)C4=C([O+]=C2C=C1NCC)C=C(NCC)C(C)=C4.[Cl-]
CAS Number
989-38-8
Target & IC50
Others
In Vitro
Compared to their untreated counterparts, Melanoma-transplanted mice receiving Rhodamine 6G demonstrate prolonged survival, inhibited tumor growth, improved clinical parameters and metastases count. It is possible to monitor changes in the interactions between leukocytes and the endothelium by determining the numbers of rolling and adhering leukocytes as well as the total flux of these cells[3]. The Rhodamine-6G enters the circulatory system and labels leukocytes. Twice-a-week 10-6M Rhodamine 6G regimen yield the most prominent results[2].

Structure of Rhodamine 6G, inhibitor

Rhodamine 6G Inhibitor – Cat# MBS5755452

Product References and Citations for Rhodamine 6G, inhibitor

Zehentbauer FM, et al. Fluorescence spectroscopy of Rhodamine 6G: concentration and solvent effects. Spectrochim Acta A Mol Biomol Spectrosc. 2014;121:147-51.
Zehentbauer FM, et al. Fluorescence spectroscopy of Rhodamine 6G: concentration and solvent effects. Spectrochim Acta A Mol Biomol Spectrosc. 2014;121:147-51.
Kutushov M, et al. Low concentrations of Rhodamine 6G selectively destroy tumor cells and improve survival of melanoma transplanted mice. Neoplasma. 2013;60(3):262-73.
Kutushov M, et al. Low concentrations of Rhodamine 6G selectively destroy tumor cells and improve survival of melanoma transplanted mice. Neoplasma. 2013;60(3):262-73.
Jain RK, et al. Measuring leukocyte-endothelial interactions in mice. Cold Spring Harb Protoc. 2013 Jun 1;2013(6):561-3.
Jain RK, et al. Measuring leukocyte-endothelial interactions in mice. Cold Spring Harb Protoc. 2013 Jun 1;2013(6):561-3.

Other Notes

Small volumes of Rhodamine 6G, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Rhodamine 6G purchase

MBS5755452 is an inhibitor targeting Rhodamine 6G.
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