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RN-18 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5755466

RN-18 is an inhibitor of HIV-1 viral infectivity factor (IC50: 6uM in nonpermissive H9 cells). More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
RN-18, Inhibitor
Full Product Name
RN-18
Product Gene Name
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
380.42
Solubility
DMSO: 97mg/mL (254.98mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C20H16N2O4S
SMILES
COc1ccccc1NC(=O)c1ccccc1Sc1ccc(cc1)[N+]([O-])=O
CAS Number
431980-38-0
Target & IC50
nonpermissive H9 cell: ic50 6uM

Structure of RN-18, inhibitor

RN-18 Inhibitor – Cat# MBS5755466

Product References and Citations for RN-18, inhibitor

Mohammed I, et al. SAR and Lead Optimization of an HIV-1 Vif-APOBEC3G Axis Inhibitor. ACS Med Chem Lett. 2012 Jun 14;3(6):465-469.
Mohammed I, et al. SAR and Lead Optimization of an HIV-1 Vif-APOBEC3G Axis Inhibitor. ACS Med Chem Lett. 2012 Jun 14;3(6):465-469.
Nathans R, et al. Small-molecule inhibition of HIV-1 Vif. Nat Biotechnol. 2008 Oct;26(10):1187-92.
Nathans R, et al. Small-molecule inhibition of HIV-1 Vif. Nat Biotechnol. 2008 Oct;26(10):1187-92.

Other Notes

Small volumes of RN-18, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RN-18 purchase

MBS5755466 is an inhibitor targeting RN-18.
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