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Selgantolimod Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5755522

Selgantolimod is an effective and selective toll-like receptor 8 agonists for the treatment,of the hepatitis B virus and human immunodeficiency virus infection. More details

Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Selgantolimod, Inhibitor
Full Product Name
Selgantolimod
Product Synonym Names
GS-9688
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
293.34
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C14H20FN5O
SMILES
C[C@@](CCCC)(CO)NC1=NC(N)=NC2=C1N=CC(F)=C2
CAS Number
2004677-13-6
Target & IC50
TLR8
HBV
In Vitro
Selgantolimod (p.o., once-weekly) treatment,induces dose-dependent increases in serum IL-12 and IL-1 receptor antagonist (IL-1RA) in cynomolgus monkeys and causes functional cure in the woodchuck model of chronic HBV [1].

Product References and Citations for Selgantolimod, inhibitor

Jules Levin. Efficacy and Safety of Oral TLR8 Agonist Selgantolimod in Virally Suppressed Adult Patients With Chronic Hepatitis B: a Phase 2, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study. 2019 Nov 8-12.
Jules Levin. Efficacy and Safety of Oral TLR8 Agonist Selgantolimod in Virally Suppressed Adult Patients With Chronic Hepatitis B: a Phase 2, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study. 2019 Nov 8-12.
Benjamin Ryan. Selgantolimod Shows Promise as treatment, for Hepatitis B. November 18, 2019.
Benjamin Ryan. Selgantolimod Shows Promise as treatment, for Hepatitis B. November 18, 2019.
Romas Geleziunas, et al. Modulators of toll-like receptors for the treatment,of hiv. US20170071944A1.
Romas Geleziunas, et al. Modulators of toll-like receptors for the treatment,of hiv. US20170071944A1.

Other Notes

Small volumes of Selgantolimod, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Selgantolimod purchase

MBS5755522 is an inhibitor targeting Selgantolimod.
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