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TC13172 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5755599

TC13172 is an inhibitor of mixed lineage kinase domain-like protein (EC50: 2nM for HT-29 cells). More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TC13172, Inhibitor
Full Product Name
TC13172
Product Gene Name
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
388.4
Solubility
DMSO: 25mg/mL (64.37mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C17H16N4O5S
SMILES
O=C1C2=C(N=C(S(C)(=O)=O)N2C)N(CC#CC3=CC(O)=CC=C3)C(N1C)=O
CAS Number
2093393-05-4
Target & IC50
MLKL, in HT-29 cells: ic50 2+/-0.6nM

Structure of TC13172, inhibitor

TC13172 Inhibitor – Cat# MBS5755599

Product References and Citations for TC13172, inhibitor

Bo Yan, et al. Discovery of a new class of highly potent necroptosis inhibitors targeting the mixed lineage kinase domain-like protein.ChemCommun (Camb). 2017 Mar 28;53(26):3637-3640.

Other Notes

Small volumes of TC13172, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TC13172 purchase

MBS5755599 is an inhibitor targeting TC13172.
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