• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

TM-N1324 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5755635

TM-N1324 is a G-Protein-Coupled Receptor 39 agonist (EC50s: 9nM/5nM in the presence of Zn2+, and 280nM/180nM in the absence of Zn2+ for human/murine GPR39). More details

Please Inquire
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TM-N1324, Inhibitor
Full Product Name
TM-N1324
Product Gene Name
TM-N1324, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
397.79
Solubility
DMSO: 6mg/mL (15.08mM) Need ultrasonic and warming
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C18H13ClFN7O
SMILES
O=C1CC(C2=CC=C(F)C=C2Cl)C3=C(N(C4=C5N=CNC5=NC=N4)N=C3C)N1
CAS Number
1144477-35-9
Target & IC50
human GPR39 without Zn2+: ic50 280nM (EC50)
human GPR39 with Zn2+: ic50 9nM (EC50)
murine GPR39 without Zn2+: ic50 180nM (EC50)
murine GPR39 with Zn2+: ic50 5nM (EC50)

Structure of TM-N1324, inhibitor

TM-N1324 Inhibitor – Cat# MBS5755635

Product References and Citations for TM-N1324, inhibitor

1. Frimurer TM, et al. Model-Based Discovery of Synthetic Agonists for the Zn2+-Sensing G-Protein-Coupled Receptor 39 (GPR39) Reveals Novel Biological Functions. J Med Chem. 2017 Feb 9;60(3):886-898.

Other Notes

Small volumes of TM-N1324, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TM-N1324 purchase

MBS5755635 is an inhibitor targeting TM-N1324.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000