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TMC353121 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5755636

TMC353121 is an effective inhibitor of respiratory syncytial virus fusion (pEC50: 9.9). More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TMC353121, Inhibitor
Full Product Name
TMC353121
Product Gene Name
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
558.71
Solubility
DMSO: 50mg/mL (89.49mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C32H42N6O3
SMILES
OC1=CC=C(C)N=C1CN2C3=CC(CNC4=CC(C)=CC=C4CCCO)=CC=C3N=C2NCCCN5CCOCC5
CAS Number
857066-90-1
Target & IC50
RSV: ic50 9.9 (pEC50)

Structure of TMC353121, inhibitor

TMC353121 Inhibitor – Cat# MBS5755636

Product References and Citations for TMC353121, inhibitor

Rouan MC, et al. Pharmacokinetics-pharmacodynamics of a respiratory syncytial virus fusion inhibitor in the cotton rat model. Antimicrob Agents Chemother. 2010 Nov;54(11):4534-9.
Olszewska W, et al. Antiviral and lung protective activity of a novel respiratory syncytial virus fusion inhibitor in a mouse model. Eur Respir J. 2011 Aug;38(2):401-8.

Other Notes

Small volumes of TMC353121, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TMC353121 purchase

MBS5755636 is an inhibitor targeting TMC353121.
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