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Toxoflavin Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5755646

Toxoflavin is an antagonist of transcription factor 4 (TCF4)/beta-catenin complex. Toxoflavin also acts as an inhibitor of KDM4A. More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Toxoflavin, Inhibitor
Full Product Name
Toxoflavin
Product Synonym Names
Xanthothricin; Toxoflavine; PKF-118-310
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
193.16
Solubility
DMSO: 25mg/mL (129.43mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C7H7N5O2
SMILES
Cn1ncnc2c1nc(=O)n(C)c2=O
CAS Number
84-82-2
Target & IC50
TCF4/beta-catenin

Product References and Citations for Toxoflavin, inhibitor

Wei W, et al. Small molecule antagonists of Tcf4/beta-catenin complex inhibit the growth of HCC cells in vitro and in vivo. Int J Cancer. 2010 May 15;126(10):2426-36.
Franci G, et al. Identification and characterization of PKF118-310 as a KDM4A inhibitor. Epigenetics. 2017 Mar 4;12(3):198-205.

Other Notes

Small volumes of Toxoflavin, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Toxoflavin purchase

MBS5755646 is an inhibitor targeting Toxoflavin.
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