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TPL2 Inhibitor – Kinase 1

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5755649

MBS5755649 is an inhibitor targeting Tpl2. Also known as Tpl2 Kinase Inhibitor 1. Tpl2 Kinase Inhibitor 1 is an effective and selective Tpl2 inhibitor. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Tpl2 Kinase 1, Inhibitor
Full Product Name
Tpl2 Kinase Inhibitor 1
Product Gene Name
Tpl2, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
404.83
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C21H14ClFN6
SMILES
N#CC1=C(NC2=CC=C(F)C(Cl)=C2)C3=CC(NCC4=CC=CN=C4)=NC=C3N=C1
CAS Number
871307-18-5
Target & IC50
MAP3K8

Structure of Tpl2, inhibitor

TPL2 Inhibitor – Cat# MBS5755649

Product References and Citations for Tpl2, inhibitor

Glatthar R, et al. Discovery of Imidazoquinolines as a Novel Class of Potent, Selective, and in Vivo Efficacious Cancer Osaka Thyroid (COT) Kinase Inhibitors. J Med Chem. 2016 Aug 25;59(16):7544-60.

Other Notes

Small volumes of Tpl2, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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