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TRAF-STOP6877002 Inhibitor – TRAF-STOP 6877002

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5755655

TRAF-STOP inhibitor 6877002, is a selective inhibitor of CD40-TRAF6 interaction. TRAF-STOP 6877002 reduces leukocyte recruitment, and reduces macrophage activation; reduces macrophage proliferation in atherosclerotic plaques. More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TRAF-STOP 6877002 (TRAF-STOP6877002), Inhibitor
Full Product Name
TRAF-STOP inhibitor 6877002
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
251.32
Solubility
DMSO: 125mg/mL (497.37mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C17H17NO
SMILES
O=C(C1=CC=CC=C1)/C=C/NC2=C(C=CC(C)=C2)C
CAS Number
433249-94-6
Target & IC50
CD40-TRAF6 interaction
NF-kappaB

Product Categories/Family for TRAF-STOP6877002, inhibitor

Product References and Citations for TRAF-STOP6877002, inhibitor

Seijkens TTP, et al. Targeting CD40-Induced TRAF6 Signaling in Macrophages Reduces Atherosclerosis. J Am Coll Cardiol. 2018 Feb 6;71(5):527-542.

Other Notes

Small volumes of TRAF-STOP6877002, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TRAF-STOP6877002 purchase

MBS5755655 is an inhibitor targeting TRAF-STOP6877002. Also known as TRAF-STOP inhibitor 6877002.
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