UPGL00004 Inhibitor

Name: UPGL00004 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5755681
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5755681

UPGL00004 inhibits the proliferation of highly aggressive triple-negative breast cancer cell lines. UPGL00004 is an effective allosteric glutaminase C inhibitor (IC50=29nM; Kd=27nM). More details

Please Inquire

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

UPGL00004, Inhibitor

Full Product Name

UPGL00004

Product Gene Name

UPGL00004, inhibitor

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

534.66

Solubility

DMSO: 125mg/mL (233.79mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C25H26N8O2S2

SMILES

O=C(NC1=NN=C(N2CCC(NC3=NN=C(NC(CC4=CC=CC=C4)=O)S3)CC2)S1)CC5=CC=CC=C5

CAS Number

1890169-95-5

Target & IC50

Glutaminase C: ic50 27nM (kd)

Product Categories/Family for UPGL00004, inhibitor

Metabolism; Others

Product References and Citations for UPGL00004, inhibitor

1. Huang Q, et al. Characterization of the interactions of potent allosteric inhibitors with glutaminase C, a key enzyme in cancer cell glutamine metabolism. J Biol Chem. 2018 Mar 9;293(10):3535-3545.

Other Notes

Small volumes of UPGL00004, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for UPGL00004 purchase

MBS5755681 is an inhibitor targeting UPGL00004.