VAL-083 Inhibitor

Name: VAL-083 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5755685
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5755685

VAL-083 is an alkylating compound that creates N7 methylation on DNA. It also has antitumor activity. More details

Please Inquire

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

VAL-083, Inhibitor

Full Product Name

VAL-083

Product Gene Name

VAL-083, inhibitor

Product Synonym Names

Dianhydrodulcitol; Dianhydrogalactitol

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

146.14

Solubility

DMF: 100mg/mL (684.28mM)
H2O: 50mg/mL (342.14mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C6H10O4

SMILES

O[C@H]([C@H](O)[C@]1(OC1)[H])[C@@]2([H])CO2

CAS Number

23261-20-3

Target & IC50

DNA Alkylator

Product Categories/Family for VAL-083, inhibitor

DNA Damage/DNA Repair; DNA Alkylation

Product References and Citations for VAL-083, inhibitor

Kaiji Hu, et al. Abstract 811: VAL083, a novel N7 alkylating agent, surpasses NSC 362856 activity and inhibits cancer stem cells providing a new potential treatment,option for glioblastoma multiforme. Cancer Research. 2012 Mar 31-Apr 4.
Jiang X, et al. Dianhydrogalactitol, a potential multitarget agent, inhibits glioblastoma migration, invasion, and angiogenesis. Biomed Pharmacother. 2017 Jul;91:1065-1074.
Peng C, et al. 1,2:5,6-dianhydrogalactitol inhibits human glioma cell growth in vivo and in vitro by arresting the cell cycle at G2/M phase. Acta Pharmacol Sin. 2017 Apr;38(4):561-570.

Other Notes

Small volumes of VAL-083, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for VAL-083 purchase

MBS5755685 is an inhibitor targeting VAL-083.